Some of you are probably involved in some sort of Windows 7 migration preparation activities and like with any operating system migration, application compatibility is one of the most important topics you will need to focus on. If you need to do a first pre-study on your application compatibility status, then I suggest you download the Windows 7 Application Compatibility List for IT Professionals and compare the content with the applications your company or client is using, this might allow you to do a first estimate on how much effort you will need to spend on Application Compatibility related tasks.
Additional Resources:
Windows 7 Compatibility Center
TechNet Application-Compatibility-Cookbook
TechNet Application Compatibility Forum